Your gut never stops moving.
It needs a protein called Ξ³-2 actin.
Ξ³-2 actin is made of 376 amino acids.
What if one amino acid was wrong?
In this example,
the Glutamine (Q) at the position 247 is replaced by a Proline (P).
This is what happens in real patients.
CIPO is a disorder where the bowels fail to move food despite no physical blockage.
Dysfunction may emerge from any point along the brainβgut axis
We explore it in 130 people.
ACTG2 is the gene behind Ξ³-2 actin.
ACTG2 wasn't the only suspect.
We genotyped hundred of unsolved cases.
Sometimes, the mutation is invisible.
Behind every mutation is a person waiting.
Discover our patients' stories.
